中华医学会器官移植分会移植基础学组委员；

四川省肿瘤协会肝癌专委会委员

作为负责人主持国家自然科学基金青年和面上项目，四川省科技厅重点研发项目，中国博士后基金面上项目以及四川大学博士后交叉学科项目等多个国家及地方科研项目。相关成果在Hepatology、Cancer Research、Theranostics、Liver International及Oncogene等国内外肝病和肿瘤学领域顶级杂志发表高水平论文20余篇。

近期代表性成果（*标注为通讯作者）：

1. Zhang B, Zhou YJ*, Xu X, Xu G, Wu Z, Wu Q, Zeng Q, Yang J, Lv T*, Yang J*. RBM39 promotes hepatocarcinogenesis by regulating RFX1's alternative splicing and subsequent activation of integrin signaling pathway. Oncogene. 2025 Jun;44(20):1488-1503.

2. Zhou YJ, Chen Y, Zhang X, Xu Q, Wu Z, Cao X, Shao M, Shu Y, Lv T, Lu C, Xie M, Wen T, Yang J*, Shi Y*, Bu H. Brahma-Related Gene 1 Inhibition Prevents Liver Fibrosis and Cholangiocarcinoma by Attenuating Progenitor Expansion. Hepatology. 2021;74(2):797-815.

3. Peng, W., Wu, Y., Zhang, X., Li, C., Shen, J., Chen, W., Li, Q., Ma, J., Yang, Y., Lu, W., Liu, Z., Sun, X., Yang, J., Zhou, Y*., & Wen, T*. (2024). Liver transplantation for advanced hepatocellular carcinoma after downstaging with consequential lenvatinib, transcatheter arterial chemoembolization and camrelizumab. Br J Surg. 2024;111(3):znae048.

4. Zhou YJ, Ji H, Xu Q, Zhang X, Cao X, Chen Y, Shao M, Wu Z, Zhang J, Lu C, Yang J*, Shi Y*, Bu H. Congenital biliary atresia is correlated with disrupted cell junctions and polarity caused by Cdc42 insufficiency in the liver. Theranostics. 2021 May 24;11(15):7262-7275.

5. Ji HJ, Zhou YJ, Zhuang X, Zhu YJ, Wu ZR, Lu YR, Li SF, Zeng Y, Lu QR, Huo YY, Shi YJ*, Bu H. HDAC3 deficiency promotes liver cancer through a defect in H3K9ac/H3K9me3 transition. Cancer Res. 2019 Jul 15;79(14):3676-3688.

6. Tan Y, Zhou Y, Zhang W, Wu Z, Xu Q, Wu Q, Yang J, Lv T, Yan L, Luo H, Shi Y*, Yang J*. Repaglinide restrains HCC development and progression by targeting FOXO3/lumican/p53 axis. Cell Oncol (Dordr). 2024 Aug;47(4):1167-1181.

7. Lv T, Zhang B, Jiang C, Zeng Q, Yang J*, Zhou Y*. USP35 promotes hepatocellular carcinoma progression by protecting PKM2 from ubiquitination‑mediated degradation. Int J Oncol. 2023;63(4):113.

8. Lv, T., Zhang, B., Xu, X., Jiang, C., Zheng, D., He, D., Zhou, Y*., & Yang, J*. (2023). Clinical prognosis and related molecular features of hepatitis B-associated adolescent and young adult hepatocellular carcinoma. Human genomics, 17(1), 52.

9. Xu Q, Liu F, Wu Z, Chen M, Zhou Y*, Shi Y*. Suppression of STK39 weakens the MASLD/MASH process by protecting the intestinal barrier. Biosci Trends. 2024 Jul 9;18(3):289-302.

10. Zhou YJ, Xu Q, Tao L, Chen Y, Shu Y, Wu Z, Lu C, Shi Y*, Bu H. Enhanced SMARCD1, a subunit of the SWI/SNF complex, promotes liver cancer growth through the mTOR pathway. Clin Sci (Lond). 2020 Jun 26;134(12):1457-1472.