袁玉佳,助理研究员,硕士生导师。2019年四川大学华西医院博士后出站留院工作。主要围绕线粒体代谢和自噬等研究免疫细胞在肾脏相关疾病中的作用及其分子机制。近年来,作为负责人主持国家自然科学青年基金、四川省科技厅项目、中国博士后基金、和校院级等多项课题。以第一/共同第一/通讯作者在Nat Commun、 Redox Biology、Theranostics、Pharmacol Res、Antioxidants & Redox Signaling等国际期刊发表高水平国际期刊论文10余篇。
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1) Yujia Yuan#, Longhui Yuan#, Jingchao Yang, Fei Liu, Shuyun Liu, Lan Li, Guangneng Liao, Xi Tang, Jingqiu Cheng, Jingping Liu, Younan Chen*, Yanrong Lu*; Autophagy-deficient macrophages exacerbate cisplatin-induced mitochondrial dysfunction and kidney injury via miR-195a-5p-SIRT3 axis. Nat Commun. 2024 May 23;15(1):4383. (共同第一作者1/2)
2) Fei Liu, Longhui Yuan, Lan Li, Jingchao Yang, Jingping Liu, Younan Chen, Jie Zhang, Yanrong Lu, Yujia Yuan*, Jingqiu Cheng. S-sulfhydration of SIRT3 combats BMSC enescence and ameliorates osteoporosis via stabilizing heterochromatic and mitochondrial homeostasis. Pharmacol Res. 2023; 192:106788. (通讯作者)
3) Longhui Yuan, Jingchao Yang, Fei Liu, Lan Li, Jingping Liu, Younan Chen, Jingqiu Cheng, Yanrong Lu*, Yujia Yuan*. Macrophage-derived exosomal miR-195a-5p impairs tubular epithelial cells mitochondria in acute kidney injury mice. FASEB J. 2023; 37(1):e22691. (共同通讯作者)
4) Jingcao Yang; Longhui Yuan; Fei Liu; Lan Li; Jingping Liu; Younan Chen; Yanrong Lu*; Yujia Yuan*; Molecular mechanisms and physiological functions of autophagy in kidney diseases. Front Pharmacol. 2022; 13: 974829. (共同通讯作者)
5) Fei Liu#; Yujia Yuan#; Lin Bai; Longhui Yuan; Lan Li; Jingping Liu; Younan Chen; Yanrong Lu; Jingqiu Cheng*; Jie Zhang*; LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss. Redox Biology.2021; 43(101963). (共同第一作者2/2)
6) Yujia Yuan; Longhui Yuan; Lan Li; Fei Liu; Jingping Liu; Younan Chen; Jingqiu Cheng; Yanrong Lu; Mitochondrial transfer from mesenchymal stem cells to macrophages restricts inflammation and alleviates kidney injury in diabetic nephropathy mice via PGC-1α activation. STEM CELLS. 2021; 39(7): 913-928.(第一作者)
7) Lingling Zhu#; Yujia Yuan#; Longhui Yuan; Lan Li; Fei Liu; Jingping Liu; Younan Chen; Yanrong Lu*; Jingqiu Cheng*; Activation of TFEB-mediated autophagy by trehalose attenuates mitochondrial dysfunction in cisplatin-induced acute kidney injury, Theranostics, 2020, 10(13):5829-5844. (共同第一作者2/2)
8) Yujia Yuan; Lingling Zhu; Lan Li; Jingping Liu; Younan Chen; Jingqiu Cheng; Tianqing Peng*; Yanrong Lu*; S-Sulfhydration of SIRT3 by Hydrogen Sulfide Attenuates Mitochondrial Dysfunction in Cisplatin-Induced Acute Kidney Injury., Antioxidants & Redox Signaling, 2019, 31(17): 1302-1319. (第一作者)
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