主持美国国防部医学研究基金、国家自然科学基金、四川省科技厅应用基础/科技人才创新/中央引导地方、天府锦城实验室前沿医学中心团队赛马、成都市科技局国际科技合作、四川大学优秀青年学者基金/创新火花、四川大学华西医院卓越学科1.3.5工程重点/临床研究孵化项目等多项科研课题。以第一或通讯作者在Advanced Materials, Cancer Research, Biomaterials, Chemical Engineering Journal, Journal of Controlled Release, Nanoscale, Advanced Healthcare Materials, Advanced Drug Delivery Review等高水平国际期刊发表学术论文40余篇,引用超过3000次。
近期代表性论文(通讯作者):
1. A redox-responsive nanosystem to suppress chemoresistant lung cancer through targeting STAT3. Journal of Controlled Release (2023)
2. Engineered extracellular vesicles-like biomimetic nanoparticles as an emerging platform for targeted cancer therapy. J Nanobiotechnology (2023)
3. Diversity-oriented synthesis of diterpenoid alkaloids yields a potent anti-inflammatory agent. Phytomedicine (2023)
4. Mitochondria-Targeting and Multiresponsive Nanoplatform Based on AIEgens for Synergistic Chemo-Photodynamic Therapy and Enhanced Immunotherapy. Biomacromolecules (2023)
5. Targeted Drug/Gene/Photodynamic Therapy via a Stimuli-Responsive Dendritic-Polymer-Based Nanococktail for Treatment of EGFR-TKI-Resistant Non-Small-Cell Lung Cancer. Adv Mater (2022)
6. Nanozymes-engineered metal–organic frameworks for enhanced microwave thermodynamic therapy in PDX of hepatic carcinoma. Chemical Engineering Journal (2022)
7. LHRH-Targeted Redox-Responsive Crosslinked Micelles Impart Selective Drug Delivery and Effective Chemotherapy in Triple-Negative Breast Cancer. Adv Healthc Mater (2021)
8. Patient-derived non-small cell lung cancer xenograft mirrors complex tumor heterogeneity. Cancer Biol Med (2021)