中华医学会乳腺肿瘤分会青年委员；

四川省医学会医学细脆生物学委员会常务委员；

四川省国际医学交流促进会人工智能与肿瘤专业委员会委员；

中国医药教育协会腹部肿瘤医学综合康复分会常务委员；

担任Military   Medical Research（IF=24.9）、MedComm   Future Medicine、Brain   X等杂志青年编委。

长期聚焦乳腺癌、胰腺癌等恶性肿瘤临床治疗的重大需求，开展以下两方面的基础与转化研究：1）利用多维基因组学结合功能基因组学研究肿瘤转移和免疫逃逸机制，筛选新的治疗靶点；2）开展以分子靶向、免疫治疗和纳米技术为核心的肿瘤精准治疗。围绕这一热点领域，开展了系统的研究，形成了特色的研究体系。近5年以通讯作者或第一作者在Cancer Cell（封面文章，ESI高被引论文）、Signal Transduction and Targeted Therapy、Cell   Discovery、Cell Reports Medicine、Advanced   Functional Material（封面文章）、Journal of Controlled Release、Journal of Investigative Dermatology、Seminars   in Cancer Biology（ESI高被引论文）等杂志发表高水平论文20余篇，单篇最高影响因子52.7。授权国家发明专利8项。承担国家自然科学基金面上项目&青年项目、国家博士后科学基金特别资助&面上项目、四川省科技计划重点研发项目、“十四五”国家重点研发计划等国家和省部级项目10项。曾获第十二届棒棰岛肿瘤前沿论坛青年创新一等奖、川渝科技学术大会优秀论文一等奖和二等奖各一次、四川省医学会2020年度优秀论文一等奖等奖励。

近五年，部分代表性论著如下：

(1)Xiaowei   Liu*; Jinen Song*;   Hao Zhang*; Xinyu Liu*; Fengli Zuo; Yunuo Zhao; Yujie Zhao; Xiaomeng Yin;   Xinyu Guo; Xi Wu; Hu Zhang; Jie Xu; Jianping Hu; Jing Jing; Xuelei Ma#;   Hubing Shi#; Immune checkpoint HLA-E:CD94-NKG2A mediates evasion of   circulating tumor cells from NK cell surveillance, Cancer Cell,   2023, 41: 1-16 (第一作者，封面文章，IF=50.6，ESI高被引论文)

(2)Xiaowei   Liu*; Fengli Zuo*;   Jinen Song*; Leyi Tang; Xueyan Wang; Xinyu Liu; Hao Zhang; Zhankun Yang; Jing   Jing#; Xuelei Ma#; and Hubing Shi#; Immune checkpoints HLA-E:CD94-NKG2A and   HLA-C:KIR2DL1 complementarily shield circulating tumor cells from NK-mediated   immune surveillance, Cell Discovery, 2024, 10:16 (第一作者，IF=33.5)

(3)Xiaowei   Liu*, Jinen Song*, Meiling Yuan, Huihui Li, Leyi Tang, Fengli Zuo, Xinmin   Wang, Xueyan Wang, Jing Jing#, Xuelei Ma#, and Hubing Shi#. Single-cell   transcriptional dissection illuminates an evolution of immunosuppressive   microenvironment during pancreatic ductal adenocarcinoma metastasis, Signal   Transduction and Targeted Therapy, 2025, 10(1):182 (第一作者，IF=52.7)

(4)Xiaowei   Liu*; Yanlin Feng*;   Guangchao Xu*; Yang Chen; Ya Luo; Jinen Song; Yu Bao; Jiqiao Yang; Chune Yu;   Yanna Li; Haoyu Ye; Bowen Ke; Bo Chen; Jianping Hu; Jie Xu; Huan Meng;   Haiyuan Zhang#; Hubing Shi# ; MAPK-Targeted Drug Delivered by a pH-Sensitive   MSNP Nanocarrier Synergizes with PD-1 Blockade in Melanoma without T-Cell   Suppression, Advanced Functional Materials, 2019, 29(12): 1-16   (第一作者，封面文章，IF=19)

(5)Xiaowei   Liu*; Yanlin Feng*;   Jie Xu*; Ying Shi; Jiqiao Yang; Rongjie Zhang; Jinen Song; Xin Bai; Xi Wu; Yu   Bao; Ya Luo; Huifang Li; Li Chai; Changyang Gong; Yan Wang; Bo Chen; Jianping   Hu; Yan Fu; Yongzhang Luo; Haiyuan Zhang#; Hubing Shi#; Combination of MAPK   inhibition with photothermal therapy synergistically augments the anti-tumor   efficacy of immune checkpoint blockade, Journal of Controlled Release,   2021, 332: 194-209 (第一作者，IF=10.8)

(6)Chen   Shi, Zhang Sirui, Shi Ying, Liu Xiaowei; Microenvironment Crosstalk   and Immune Evasion of Circulating Tumor Cells: from Mechanism to Clinical   Significance, Chinese Medical Journal, 2025,   (通讯作者，IF=7.3)

(7)Xiujing   He*; Xiaowei Liu*; Fengli Zuo; Hubing Shi; Jing Jing; Artificial   intelligence based multi-omics analysis fuels cancer precision medicine, Seminars   in Cancer Biology, 2022, 88: 187-200 (共同第一作者，IF=14.5，ESI高被引论文)

(8)Xueyan   Wang*; Jing Yu*; Xiaowei Liu*; Dan Luo; Yanchu Li; Linlin Song; Xian   Jiang; Xiaomeng Yin; Li Chai; Ting Luo; Jing Jing#; Hubing Shi#;   PSMG2-controlled proteasome-autophagy balance mediates the tolerance for   MEK-targeted therapy in triple-negative breast cancer, Cell Reports   Medicine, 2022, 9: 100741-100741 (共同第一作者，IF=14.3)

(9)Jing   Yu; Xi Wu; Jinen Song; Yujie Zhao; Huifang Li; Min Luo; Xiaowei Liu;   Loss of MHC-I antigen presentation correlated with immune checkpoint blockade   tolerance in MAPK inhibitor resistant melanoma., Frontiers   in Pharmacology, 2022, 13 (通讯作者，IF=5.6)

(10)Yujie Zhao; Xu Liu; Xinyu Liu; Jie Yu; Xin Bai; Xi   Wu; Xinyu Guo; Zhihui Liu; Xiaowei Liu; Combination of phototherapy   with immune checkpoint blockade: Theory and practice in cancer, Frontiers   in Immunology, 2022, 13 (通讯作者，IF=7.3)

(11)Xu   Liu; Yujie Zhao; Xi Wu; Zhihui Liu; Xiaowei Liu; A novel strategy to   fuel cancer immunotherapy: targeting glucose metabolism to remodel the tumor   microenvironment, Prime Archives in Cancer Research (通讯作者，Book chapter)