四川省学术和技术带头人后备人选

四川省医学会精准医学专业委员会秘书

四川省国际医学交流促进会人工智能与肿瘤专业委员会常委

以第一作者/通讯作者在Nat. Commun., Signal Transduct Target Ther.，Cancer Res和 Cell Reports等杂志发表高水平论文40余篇。先后主持国家自然科学基金3项、四大慢病国家科技重大专项子课题、国家博士后特别资助基金和四川省科技厅重点项目基金等项目20余项。

代表性论文： 

1) C Cheng, GN Zhu, YQ Li, HY Wang, SY Wang, CP Li, JM Feng, ZF Wang*, WM Li*. Single-cell transcriptome analysis reveals cellular and molecular alterations in small cell lung cancer tumors following chemotherapy. Int J Cancer. 2023 Jun 19. 

2) ZF Wang, KH Xie, GN Zhu, CC Ma, CC Cheng, YQ Li, X Xiao, CP Li, J Tang, H Wang, ZX Su, D Liu, WG Zhang, Y Huang, HR Tang, R Liu* and WM Li*. Early detection and stratification of lung cancer aided by a cost-effective assay targeting circulating tumor DNA (ctDNA) methylation. Respir Res. 2023 Jun 17;24(1):163.   

3) Z Cui#, WX Luo#, RH Chen#, YL Li#, ZF Wang#, Y Liu#, S Liu, LL Feng, ZJ Jia, RX Cheng, J Tang, WJ Huang, YJ Zhang, HW Liu*, XX Wang* and WM Li*. Comparing T- and B-cell responses to COVID-19 vaccines across varied immune backgrounds. Signal Transduct Target Ther. 2023. 8(1):179. 1. 

4) Q Zhang, XM Tang, YJ Zhao, ZF Wang* Team-based learning vs.lecture-based learning in nursing: A systematic review of randomized controlled trials. Front Public Health. 2023 Jan 4; 10:1044014. 

5) Y Zhao#, QL Zhang#, KL Tu, YM Chen, YX Peng, YY Ni, GN Zhu, C Cheng, YQ Li, X Xiao, CY Yu, KY Lu, YX Chen, CP Li, J Tang, G Wang, WX Luo, WG Zhang, GW Che, WM Li, ZF Wang* and D Xie*. Single-Cell Transcriptomics of Immune Cells Reveal Diversity and Exhaustion Signatures in Non-Small-Cell Lung Cancer. Front Immunol. 2022. 13:854724. 

6) ZF Wang#, Z Li#, K Zhou#, CD Wang#, LL Jiang, L Zhang, Y Yang, WX Luo, WL Qiao, G Wang, YY Ni, SP Dai, TT Guo, GY Ji, MJ Xu, YY Liu, ZX Su, GW Che*, and WM Li*. Deciphering cell lineage specification of human lung adenocarcinoma with single-cell RNA sequencing. Nat Commun. 2021. 12:6500. 

7) L Xia#, ZF Wang#, XY Wu#, TF Zeng#, WX Luo, XL Hu, YY Ni, GW Che, LX Liu, W Zhang, D Xie* and WM Li*. Multiplatform discovery and regulatory function analysis of structural variations in non-small cell lung carcinoma. Cell Rep. 2021. 36(10):109660. 

8) CD Wang#, ZF Wang#, GY Wang#, Johnson YN Lau*, K Zhang*, WM Li*. COVID-19 in early 2021: current status and looking forward. Signal Transduction and Targeted Therapy. 2021, 6(114): 1-14. 

9) ZF Wang #, KL Tu#, L Xia#, K Luo#, WX Luo#, J Tang, KY Lu, XL Hu, YJ He, WL Qiao, YZ Zhou, J Zhang, F Cao, SP Dai, PW Tian, Y Wang, LX Liu, GW Che, QH Zhou, D Xie∗, and WM Li∗. The Open Chromatin Landscape of Non–Small Cell Lung Carcinoma. Cancer Res. 2019, 79(19): 4840-4854.