四川省免疫学会理事；: Signal Transduction and Targeted Therapy，Phytomedicine，Autophagy，Acta Pharmacologica Sinica等高水平国际期刊审稿人。

研究方向为糖尿病及其并发症的病理生理及其干预。探索营养干预、干细胞移植等在治疗糖尿病及非酒精性脂肪肝病等代谢性疾病中的作用及其机制。主持“863”计划子课题1项，NSFC面上项目2项、青年基金1项，四川省科技厅国际合作项目2项，及教育部博士后一等资助等。参与课题组863、973课题、NSFC重点课题等多项课题的研究工作。近年来已发表论文50余篇，其中第一/通讯作者在Nat.Commun、Stem Cells、Liver International等杂志以第一/通讯作者发表高水平国际期刊论文30余篇，参编研究生教材或专著5部（包括全英文1部）。授权国家发明专利2项，申请PCT专利2项。

近年来主要发表论文：

1.  Shan Su, Xiaohong Liu, Min Zhu, Wen Liu, Jingyi Liu, Yujia Yuan, Fudong Fu, Zhiyong Rao,Jingping Liu, Yanrong Lu, and Younan Chen*，Trehalose Ameliorates Nonalcoholic Fatty Liver Disease by Regulating IRE1α−TFEB Signaling Pathway. Journal of Agricultural and Food Chemistry, 2025, Jan 8;73(1):521-540.

2.Xin Zeng, Tian Wu, Qing Xu1, Lan Li, Yujia Yuan, Min Zhu, Wen Liu, Fudong Fu, Zhenru Wu, Han Yao, Guangneng Liao, Yanrong Lu, Jingqiu Cheng, Jingping Liu, Yujun Shi, Younan Chen. Inhibition of IRE-1α alleviates pyroptosis and metabolic dysfunction-associated steatohepatitis by suppressing gasdermin D. Liver International , 2025, Feb;45(2):e16234.

3.Yujia Yuan , Longhui Yuan, Jingchao Yang, Fei Liu, Shuyun Liu, Lan Li, Guangneng Liao, Xi Tang, Jingqiu Cheng, Jingping Liu, Younan Chen*, Yanrong Lu*, Autophagy-deficient macrophages exacerbate cisplatin-induced mitochondrial dysfunction and kidney injury via miR-195a-5p-SIRT3 axis. 2024, Nat Commun, 2024 May 23;15(1):4383

4.Wen Liu, Min Zhu, Jingyi Liu, Shan Su, Xin Zeng,Fudong Fu, Yanrong Lu, Zhiyong Rao* and Younan Chen*,Comparison of the effects of monounsaturated fatty acids and polyunsaturated fatty acids on the lipotoxicity of islets. Front. Endocrinol. 2024, 15:1368853

5.Wen Liu, Min Zhu, Meng Gong, Wen Zheng, Xin Zeng, Qing Zheng, Xiaoyu Li, Fudong Fu, Yingyi Chen, Jingqiu Cheng, Zhiyong Rao, Yanrong Lu * and Younan Chen*, Comparison of the Effects of Monounsaturated Fatty Acids and Polyunsaturated Fatty Acids on Liver Lipid Disorders in Obese Mice. Nutrients, 2023, 15, 3200

6.Qing Zheng, Min Zhu, Xin Zeng, Wen Liu, Fudong Fu, Xiaoyu Li, Guangneng Liao, Yanrong Lu, and Younan Chen*.Comparison of Animal Models for the Study of Nonalcoholic Fatty Liver Disease, Lab Invest, 2023, Jul;103(7):100129.

7.Linzhao Li, Xin Zeng，Zhenzhen Liu, Xuanming Chen, Lan Li, Ruixi LuoXiaohong Liu, Jie Zhang, Jingping Liu, Yanrong Lu,Jingqiu Cheng*, Younan Chen*. Mesenchymal stromal cells protect hepatocytes from lipotoxicity through alleviation of endoplasmic reticulum stress by restoring SERCA activity. J Cell Mol Med, 2021, 25:2976–2993

8.Ruixi Luo, Linzhao Li, Xiaohong Liu, Yujia Yuan, Wuzheng Zhu, Lan Li, Jingping Liu, Yanrong Lu, Jingqiu Cheng*, Younan Chen*. Mesenchymal stem cells alleviate palmitic acid induced endothelial to mesenchymal transition by suppressing endoplasmic reticulum stress. AJP-Endocrinology and Metabolism , 2020, Dec 1;319(6):E961-E980

9.Yujia Yuan, Lan Li, Linlin Zhu, Fei Liu, Xi Tang, Guangneng Liao, Jingping Liu, Jingqiu Cheng, Younan Chen*, Yanrong Lu*. Mesenchymal stem cells elicit macrophages into M2 phenotype via improving transcription factor EB-mediated autophagy to alleviate diabetic nephropathy. Stem cells. 2020, 38(5): 639-652 doi: 10.1002/stem.3144