无

目前主持的科学基金项目：

(1) 国家自然科学基金委员会, 青年科学基金项目, 52203178, 可主动穿透血脑屏障的生物活性诊疗系统 的构建及其在脑胶质母细胞瘤术后放化疗中的应用, 2023-01-01 至 2025-12-31, 30万元, 在研, 主持

(2) 中国博士后科学基金，面上资助，2023M732438，仿生铜基纳米治疗系统诱发铜死亡介导脑胶质母细胞瘤免疫治疗的研究，2023-06-01至2025-06-30，8万，在研，主持

(3) 四川省博士后科研项目特别资助，特等资助，TB2023005，仿生铜基纳米治疗系统诱发铜死亡介导脑胶质母细胞瘤免疫治疗的研究，2023-06-01至2025-06-30，20万，在研，主持

近5年发表论文：

（1）ChengYuan Dong* , QianXiao Huang* , Han Cheng , DiWei Zheng , Sheng Hong , Yu Yan , MeiTing Niu , JianGuo Xu , XianZheng Zhang . Neisseria meningitidis Opca Protein/MnO2 Hybrid Nanoparticles for Overcoming the Blood–Brain Barrier to Treat Glioblastoma, Advanced Materials,2022, Jan 7:e2109213. (IF 30.849)

（2）QianXiao Huang , JunLong Liang , QiWen Chen , XiaoKang Jin , MeiTing Niu , ChengYuan Dong# , XianZheng Zhang# . Metal-organic framework nanoagent induces cuproptosis for effective immunotherapy of malignant glioblastoma. Nano Today, 2023, Volume 51,101911.( IF 17.4)

（3）QianXiao Huang, JunLong Liang, MeiTing Niu, XiaoKang Jin, ChengYuan Dong#, SiXue Cheng#, XianZheng Zhang#. Interfering tumor metabolism by bimetallic nanoagent for amplifying nanocatalytic-mediated glioblastoma immunotherapy. Nano Today, 2024,Volume 56,102253. (IF 17.4)

（4）ChengYuan Dong, Hong S, Zheng DW, Huang QX, Liu FS, Zhong ZL, Zhang XZ. Multifunctionalized Gold Sub-Nanometer Particles for Sensitizing Radiotherapy against Glioblastoma. Small. 2020 Dec 31; e2006582.

（5）ChengYuan Dong, Zhou Q, Xiang JJ, Liu FS, Zhou ZX, Shen YQ. Self-assembly of oxidation-responsive polyethylene glycol-paclitaxel prodrug for cancer chemotherapy. J Control Release. 2020 May 10;321:529-539.

（6）Zhou Q, ChengYuan Dong, Fan WF, Jiang HP, Xiang JJ, Qiu NS, Piao Y, Xie T, Luo YW, Li ZC, Liu FS, Shen YQ. Tumor extravasation and infiltration as barriers of nanomedicine for high efficacy: The current status and transcytosis strategy. Biomaterials. 2020 May; 240: 119902.

（7）Hu SQ, ChengYuan Dong, Wang JQ, Liu KX, Zhou Q, Xiang JJ, Zhou ZX, Liu FS, Shen YQ. Assemblies of indocyanine green and chemotherapeutic drug to cure established tumors by synergistic chemo-photo therapy. J Control Release. 2020 Aug 10;324:250-259.

（8）ChengYuan Dong, Zhang JW, Fang S, Liu FS. IGFBP5 increases cell invasion and inhibits cell proliferation by EMT and Akt signaling pathway in Glioblastoma multiforme cells. Cell Div. 2020 Feb 27;15:4.

（9）ChengYuan Dong, Fan WH, Fang S. PBK as a Potential Biomarker Associated with Prognosis of Glioblastoma. J Mol Neurosci. 2020 Jan;70(1):56-64.