中国医师协会神经介入专委会脑出血学组副组长

中国研究型医院学会神经再生与修复专业委员会委员

Ø 近年学术成果

以第一作者和通讯作者（含共同）在Lancet, J stroke, Int J stroke, Neurology等期刊发表SCI论文30篇，单篇最高影响因子88.5，部分罗列如下：

1. Ma L, Hu X, Song L, et al. The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial. Lancet. 2023;402(10395):27-40. <标志性成果>，共同第一作者

2. Hu X, Ouyang M, Xu J, et al. Surgical outcomes from haematoma evacuation for intracerebral haemorrhage in the INTERACT3 study. Lancet Reg Health West Pac. 2025;62:101669. <柳叶刀子刊>第一作者

3. Huan J, Yao M, Ma Y, et al. Surgical interventions for spontaneous supratentorial intracerebral haemorrhage: a systematic review and network meta-analysis. eClinicalMedicine. 2025;79:102999 <柳叶刀子刊>通讯作者

4. Ren X, Li Q, Ouyang M, et al. Mediation Analysis to Identify Individual Component Effects of the Care Bundle to Improve Functional Outcome After ICH in the INTERACT3 Study. Neurology. 2025;105(7):e214070. 通讯作者

5. Fang M, Xia F, Teng B, et al. RvE1/ChemR23 facilitates hematoma clearance and promotes M2 polarization of macrophages/microglia in intracerebral hemorrhage. Exp Neurol. 2025;386:115173. 通讯作者

6. Fang M, Xia F, Wang J, et al. The NLRP3 inhibitor, OLT1177 attenuates brain injury in experimental intracerebral hemorrhage. Int Immunopharmacol. 2024;131:111869. 通讯作者

7. Hu X, Fang M, Tao C, et al. New era for intracerebral haemorrhage management: Lessons from INTERACT3. Clin Transl Med. 2023;13(10):e1419. 第一作者

8. Fang M, Wang J, Wang Z, et al. Impact of hypertensive disorders of pregnancy on short- and long-term outcomes of pregnancy-associated hemorrhagic stroke. Front Neurol. 2023;14:1097183. 通讯作者

9. Chen Y, Fang M, Wu P, et al. Seizure prophylaxis following aneurysmal subarachnoid haemorrhage (SPSAH): study protocol for a multicentre randomised placebo-controlled trial of short-term sodium valproate prophylaxis in patients with acute subarachnoid haemorrhage. BMJ Open. 2022;12(5):e057917. 通讯作者

10. Wang T, Li J, Hu X, Zheng S. Rapid Disappearance of Acute Unilateral Epidural Hematoma Due to Compression of Contralateral Subdural Hematoma. Neurology. 2021;97(22):1031-2. 通讯作者

11. Li Y, Wen D, Cui W, et al. The Prognostic Value of the Acute Phase Systemic Immune-Inflammation Index in Patients With Intracerebral Hemorrhage. Front Neurol. 2021;12:628557. 通讯作者

12. Chen Y, Xia F, Li Y, et al. Changes in Characteristics, Treatment and Outcome in Patients with Hemorrhagic Stroke During COVID-19. J Stroke Cerebrovasc Dis. 2021;30(3):105536. 通讯作者

13. Chen Y, Xia F, Cai C, et al. Duration and choices of prophylactic anticonvulsants in subarachnoid hemorrhage: a systematic review and meta-analysis. Neurosurg Rev. 2021;44(5):2459-67. 通讯作者

14. Xia F, Yu X, Li Y, et al. Geographic Variations of Stroke Incidence in Chinese Communities: An 18-Year Prospective Cohort Study from 1997 to 2015. J Stroke. 2020;22(3):345-56. 通讯作者

Ø 课题

1. 国家自然科学基金面上项目1项；

2. 四川省科技厅重点研发项目1项；

3. 四川省卫健委科技项目1项；

4. 国家自然科学基金青年基金1项；

5. 四川大学华西医院临床孵化项目1项；

Ø 获奖

四川省科技进步一等奖（2025年，第二完成人）

华夏医学科技奖二等奖

Ø 指南、共识执笔

《出凝血功能障碍相关性脑出血中国多学科诊治指南》：执笔

《急性脑损伤生物标志物临床应用专家共识》：执笔