课题名称
基于核酸诊断技术的包虫病个体化治疗、精准防控及成效评估
基于分子靶向、分子影像和分子病理分型的肝癌精准治疗研究
TXNDC12通过上调β-catenin促进肝癌转移的分子机制研究
成都生物医学材料产业创新示范
生物医学材料检验评价和临床应用服务平台构建
建立肝癌多学科综合防治的华西模式
MINA53通过上调ASPM促进肝再生的作用及机制研究
LncRNA TLNC1通过调控β-catenin促进肝癌发生发展的作用及机制研究
包虫病全病程精准治疗项目在西藏自治区应用示范
KIAA1429通过m6A-RNA甲基化调控circDLC1促进肝癌复发和转移的机制研究
基于核酸诊断技术包虫病超早期诊疗方案及推广
获奖荣誉
获教育部科学技术进步奖二等奖1次；华夏科技奖一等奖1次；中华医学科学技术进步奖三等奖1次。
出版著作
《腹部外科手术要点及围手术期处理》《活体肝移植》《幕内肝脏外科学》、；
近期论文：
Lan T, Yuan K, Yan X, Xu L, Liao H, Hao X, Wang J, Liu H, Chen X, Xie K, Li J, Liao M, Huang J, Zeng Y, Wu H*. LncRNA SNHG10 Facilitates Hepatocarcinogenesis and Metastasis by Modulating Its Homolog SCARNA13 via a Positive Feedback Loop. Cancer Res. 2019 Jul 1;79(13):3220-3234
Yuan KF, Xie KL…Wu H. TXNDC12 promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma cells via activation of β-catenin. Cell death & differentiation, 2019,in press
Xie K, Chen CH, Tsai SP, Lu PJ, Wu H, Zeng Y, Ye Y, Tu H, Wen C, Huang M, Zhang Y, Lee JH, Tsai MK, Wen CP, Wu X. Loss of Life Expectancy by 10 Years or More From Elevated Aspartate Aminotransferase: Finding Aspartate Aminotransferase a Better Mortality Predictor for All-Cause and Liver-Related than Alanine Aminotransferase. Am J Gastroenterol. 2019 Sep;114(9):1478-1487
Yan X, Wan H, Hao X, Lan T, Li W, Xu L, Yuan K, Wu H*. Importance of gene expression signatures in pancreatic cancer prognosis and the establishment of a prediction model. Cancer Manag Res. 2018 Dec 27;11:273-283
Li W, Han J, Xie G, Xiao Y, Sun K, Yuan K, Wu H*. Laparoscopic versus open mesohepatectomy for patients with centrally located hepatocellular carcinoma: a propensity score matched analysis. Surg Endosc. 2019 Sep;33(9):2916-2926
Xie K, Xu L, Wu H, Liao H, Luo L, Liao M, Gong J, Deng Y, Yuan K, Wu H*, Zeng Y. OX40 expression in hepatocellular carcinoma is associated with a distinct immune microenvironment, specific mutation signature, and poor prognosis. Oncoimmunology. 2018 Mar 6;7(4):
Li W, Li L, Minigalin D, Wu H*. Anatomic mesohepatectomy versus extended hepatectomy for patients with centrally located hepatocellular carcinoma. HPB (Oxford). 2018 Jun;20(6):530-537
Li W, Li L, Han J, Wu H*. Liver transplantation vs liver resection in patients with HBV-related hepatocellular carcinoma beyond Milan criterion: A meta-analysis. Clin Transplant. 2018 Mar;32(3):e13193
Xie KL, Zhang YG, Liu J, Zeng Y, Wu H*. MicroRNAs associated with HBV infection and HBV-related HCC.Theranostics. 2014 Sep 19;4(12):1176-92.
Xie KL, Zeng Y, Wu H*. Hepatic trisectionectomy for hepatocellular carcinoma using the Glisson pedicle method combined with anterior approach. World J Surg. 2014 Sep;38(9):2358-62
